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HERDIN Record #: 108908-19070917025777 Submitted: 10 July 2019 Modified: 10 July 2019

Maxillary Sinus Squamous Cell Carcinoma in a Tertiary Hospital in the Philippines.

Anna Kristina  M. Hernandez,
Arsenio Claro A. Cabungcal

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Objective: To establish preliminary demographic and clinicopathologic data on Maxillary Sinus Squamous Cell Carcinoma (SCC) in the Philippine General Hospital


Design:           Retrospective Case Series

Setting:           Tertiary National University Hospital

Participants: Socio-demographic and clinical data from records of 22 patients admitted at the Department of Otorhinolaryngology of the Philippine General Hospital from 2013-2016 and histopathologically confirmed to have Maxillary Sinus SCC, were collected and described using means and proportions.

Results: There were 15 males and 7 females with a mean age of 50-years-old (range 24 to 77-years-old). Maxillary mass/swelling was the most common chief complaint.  The mean gap between initial symptoms and consult was 6.77 months.  Initial biopsies were obtained from the maxillary sinus in 16 patients, with 1 patient noted to have undergone malignant transformation from a prior intranasal squamous papilloma.  Staging was advanced (Stage IVA in 16, IVB in 4, and III in 2), with no patients with Stage I or II disease.  Sixteen (16) patients underwent surgery and radiotherapy, while 6 patients received radiotherapy (RT) with or without chemotherapy.  Regional and distant metastases were uncommon.

Conclusion: In this series, maxillary sinus SCC occurs more in males, with a maxillary mass as the most common chief complaint.  Delay in treatment is common, with a mean gap of 6 months between initial symptoms and consult.  Neck node metastasis is uncommon, and most patients undergo surgery with radiotherapy as treatment.


Keywords: maxillary sinus cancer; paranasal sinus cancer; squamous cell carcinoma

Publication Type
Publication Sub Type
Journal Article, Original
Philippine Journal of Otolaryngology Head and Neck Surgery
Publication Date
January-June 2019
LocationLocation CodeAvailable FormatAvailability
Philippine Society of Otolaryngology-Head and Neck Surgery Fulltext pdf (Download)
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1. Pilch, B , Bouquot, J , Thompson, . Squamous cell carcinoma. World Health Organizationclassification of tumours: Pathology and genetics of head and neck tumours Geneva: IARC Press, 2005. 15-17.