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Submitted: 18 April 2016 Modified: 28 April 2016
HERDIN Record #: PCHRD16041810101550

Papillary thyroid carcinoma identified on bone scan with SPECT/CT in a patient presenting with multiple bone metastases.

Angelica A. Barrenechea,
Gerard L. Goco,
Irene S. Bandong

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This is a case report of a 65-year-old female with lumbar vertebral lesions secondary to an unknown primary malignancy. 99mTc-methylene diphosphonate bone scintigraphy showed multiple bone metastases as well as focal extraosseous uptake in the area above the right supraclavicular area. Further imaging with SPECT/CT localized the calcified extraosseous uptake to the right thyroid bed. These findings narrowed down the primary malignancy to a thyroidal origin, which was eventually proven as such through immunohistologic studies of the lumbar lesions. Different pathophysiologic mechanisms of extraosseous uptake in bone scintigraphy and how SPECT/CT can increase the diagnostic value of a standard nuclear medicine procedure are highlighted in this paper.

Publication Type
Journal
Publication Sub Type
Case report
Title
The Philippine Journal of Nuclear Medicine
Frequency
Semi-Annual
Publication Date
July-December 2015
Volume
10
Issue
2
Page(s)
44-48
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 21 Fulltext pdf (Request Document)