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HERDIN Record #: PCHRD15012002292995 Submitted: 20 January 2015 Modified: 15 January 2018

Sonographic findings predictive of early pregnancy loss: A retrospective review.

Jacky Lou F. Macapagal,
Brenda Bernadette B. Zamora

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The objective of this study was to determine if abnormal sonographic findings among live embryo are predictive of early pregnancy loss.

METHODS: This was a retrospective cohort analytic study involving 419 pregnant women with viable first trimester pregnancy transvaginal sonographic examination. Sonographic characteristics of the choriodecidual appearance, gestational sac position, yolk sac size, fetal heart rate, subchorionic hemorrhage and laterality of the corpus luteum were noted. The clinical outcome of pregnancy loss of less than 12 weeks' gestation occurred following the sonogram. Univariate and multivariate logistic regression analyses were performed to estimate odds ratios for the independent predictor variables in the study. Sensitivity, specificity and accuracy were computed.

RESULTS: Irregular choriodecidual appearance, low gestational sac, micro yolk sac, presence of subchorionic hemorrhage and literality of corpus luteum formation were not significantly associated with early pregnancy loss. Fetal bradycardia

CONCLUSION: Sonograpic finding of fetal bradycardia ≤100bpm is a predictor of early pregnancy loss. It may be recommended that a woman with a viable early first trimester gestation with fetal bradycardia should have a repeat sonogram later in the first trimester to re-assess fetal viability.

Publication Type
Publication Sub Type
Journal Article, Original
Philippine Journal of Obstetrics and Gynecology
Publication Date
April-June 2013
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box no. 52A Fulltext pdf (Request Document)