OBJECTIVE: To determine whether infants of gestational diabetes mellitus (gdm) mother who were large for gestational age (lga) were at a higher risk of developing obesity in 1-5 years of age and to present other factors that influence obesity in this population.
DESIGN: Retrospective cohort study
SETTING: St. Luke's Medical Center, Metro Manila, Philippines
METHOD: The study population was composed of children 1-5 years old born to GDM mothers from 2002-2006, whose gestational age was at least 34 weeks, with normal development, and no hypertension or diabetes mellitus. Baseline information extracted from self administered questionnaires and the medical records included the body-mass-index (BMI) of mothers and children, treatment for GDM, smoking habits, socio-economic status, breastfeeding and eating habits. Pearson Chi-square method and logic regression method used in data analysis.
RESULT: Thirty-three subjects included in the study were divided into the obese and non-obese groups. Multivariate analysis showed that maternal overweight or obesity significantly predicts early childhood obesity (p=0.05), with the risk of nearly two times as much in a child with an obese mother than a child whose mother was not obese (RR=1.99; 95% CI=1.19-3.32). There were no significant risks for obesity for the other variables (socio-ecomics, GDM status, smoking habit, breastfeeding and eating habits; p>0.05).
CONCLUSION: Birth weight was not a significant factor in predicting early childhood obesity. Maternal BMI was significantly associated with early childhood obesity. The higher the maternal BMI, the more likely will the child become obese at 1-5 years of age.